Fig. 5
From: Circadian rhythm perturbation causes IBS-like characteristics and altered fecal metabolome in mice

Light/dark phase shift disturbed metabolism of gut microbiota. Volcano plots showed differential metabolites between NN and PN in the (A) positive and (B) negative modes of untargeted metabolomics analysis. Red and green dots represent upregulated and downregulated metabolites in PN compared with NN, respectively. NN, Non-phase shift; PN, light/dark phase shift