Table 1 The antibiotic susceptibility of different Klebsiella strains sequenced in this study
Antibiotic class | Antibiotic Sub-class | Antibiotic | K. michiganensis | K. pasteurii | K. grimontii | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NGB-FR1 | NGB-FR3 | NGB-FR19 | NGB-FR89 | NGB-FR129 | NGB-FR49 | NGB-FR50 | NGB-FR52 | NGB-FR108 | NGB-FR21 | NGB-FR40 | NGB-FR67 | NGB-FR100 | NGB-FR111 | |||
β-lactam Penicillins | Aminopenicillins | Ampicillin | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) |
β-lactam Cephems | Cephalosporins III | Ceftazidime | R (15) | R (10) | R (16) | R (0) | R (16) | I (20) | R (12) | R (11) | R (10) | S (22) | S (21) | R (10) | S (21) | R (10) |
β-lactam Penems | Carbapenems | Meropenem | S (30) | S (39) | S (32) | S (32) | S (30) | S (39) | S (38) | S (34) | S (34) | S (37) | S (39) | S (36) | S (37) | S (33) |
β-lactam combination agents | - | Amoxicillin/ Clavulanic acid | R (0) | R (0) | R (12) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) | R (0) |
- | Piperacillin/ Tazobactam | S (25) | S (30) | S (26) | S (27) | S (26) | S (30) | S (27) | S (28) | S (24) | S (26) | S (27) | S (25) | S (28) | S (23) | |
β-lactam monobactams | - | Aztreonam | S (31) | S (31) | S (29) | S (32) | S (31) | S (34) | S (33) | S (32) | S (35) | S (29) | S (29) | S (29) | S (30) | S (32) |
Non-β-Lactam Aminoglycoside | - | Amikacin | S (24) | S (20) | S (24) | S (24) | S (24) | S (20) | S (21) | S (18) | S (19) | S (23) | S (21) | S (21) | S (19) | S (25) |
- | Gentamicin | S (22) | S (22) | S (21) | S (21) | S (24) | S (20) | S (22) | S (21) | S (21) | S (21) | S (23) | S (23) | S (23) | S (22) | |
Non-β-Lactam Fluoroquinolone | Fluoroquinolones | Ciprofloxacin | S (41) | S (38) | S (39) | S (40) | S (38) | S (39) | S (37) | S (41) | S (39) | S (40) | S (40) | S (40) | S (42) | S (35) |
Fluoroquinolones | Levofloxacin | S (34) | S (36) | S (34) | S (35) | S (33) | S (31) | S (35) | S (37) | S (35) | S (38) | S (39) | S (36) | S (41) | S (34) | |
Non-β-Lactam Phenicol | - | Chloramphenicol | S (33) | S (31) | S (30) | S (33) | S (32) | S (29) | S (30) | S (30) | S (31) | S (27) | S (27) | S (29) | S (29) | S (27) |
Non-β-Lactam Folate pathway antagonists | Combination | Trimethoprim/ Sulfamethoxazole | S (27) | S (31) | S (29) | S (29) | S (28) | S (31) | S (30) | S (27) | S (26) | S (30) | S (28) | S (26) | S (27) | S (33) |