Table 1 Metabolites with intergroup differences in fecal samples
Compounds | Class | HC vs. SLE-nonLN | SLE-nonLN vs. SLE-LN | ||||||
|---|---|---|---|---|---|---|---|---|---|
VIP | FC | p | Trend | VIP | FC | p | Trend | ||
Glycocholic acid | Bile acids | 2.99 | 5.06 | 0.00 | ↑ | 3.10 | 0.37 | 0.00 | ↓ |
5,8,11-Eicosatrienoic acid | Fatty Acyls | 1.66 | 0.31 | 0.01 | ↓ | 1.80 | 3.11 | 0.00 | ↑ |
Stachydrine | Amino acid and Its metabolites | 1.23 | 4.31 | 0.03 | ↑ | — | — | — | — |
Glycine deoxycholic acid | Organic acid And Its derivatives | 1.83 | 11.02 | 0.04 | ↑ | — | — | — | — |
Glycochenodeoxycholic acid | Bile acids | 2.52 | 8.88 | 0.00 | ↑ | 2.56 | 0.28 | 0.01 | ↓ |
Methylsuccinic acid | Organic acid And Its derivatives | — | — | — | — | 1.06 | 0.35 | 0.02 | ↓ |
Palmitoylcarnitine | Alkaloids | — | — | — | — | 1.28 | 2.78 | 0.03 | ↑ |
Ursocholic acid | Bile acids | — | — | — | — | 1.41 | 6.95 | 0.02 | ↑ |
Oxypurinol | Heterocyclic compounds | — | — | — | — | 1.54 | 0.15 | 0.04 | ↓ |