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Table 5 Agreement between antibiotic resistance genotypes and phenotypes of in H. pylori strains isolated in Vietnam

From: Identification of genetic determinants of antibiotic resistance in Helicobacter pylori isolates in Vietnam by high-throughput sequencing

Antibiotic

Mutations

Phenotype

Cohen’s kappa (95%CI)

Resistant

Susceptible

n (%)

n (%)

AMX (pbp1 A)

Resistant (mutation)

17 (100)

3 (29.2)

0.90 (0.796;1)

Susceptible (no mutation)

0

93 (70.7)

CLR (23S rRNA)

Resistant (mutation)

52 (96.3)

1 (1.4)

0.95 (0.89;1)

Susceptible (no mutation)

2 (3.7)

68 (95.5)

LVX (gyrA)

Resistant (mutation)

24 (85.7)

16 (16.8)

0.6 (0.44; 0.75)

Susceptible (no mutation)

4 (14.2)

79 (83.1)

MTZ (rdxA)

Resistant (mutation)

91 (100)

8 (100)

0.81 (0.69; 0.93)

Susceptible (no mutation)

0

24 (0)