Gut microbiome links obesity to type 2 diabetes: insights from Mendelian randomization

BMC Microbiology

Table 2 The shared taxa between type 2 diabetes (T2D) and body mass index (BMI)

Exposure	Outcome	Source	OR [95%CI]
Genus Coprobacter	BMI	DMP	0.97 [0.95–0.99]
Genus Coprobacter	T2D	DMP	0.93 [0.89–0.97]
Species Coprobacter_fastidiosus	T2D	DMP	0.93 [0.89–0.97]
Species Coprobacter_fastidiosus	BMI	DMP	0.97 [0.95–0.99]
Family Oscillospiraceae	T2D	DMP	1.09 [1.01–1.18]
BMI	Family Oscillospiraceae	DMP	1.14 [1.03–1.27]
Genus Oscillibacter	T2D	DMP	1.08 [1.01–1.16]
BMI	Genus Oscillibacter	DMP	1.14 [1.03–1.27]
Species Oscillibacter_unclassified	T2D	DMP	1.09 [1.01–1.18]
BMI	Species Oscillibacter_unclassified	DMP	1.14 [1.03–1.27]
Species Veillonella_unclassified	T2D	DMP	0.96 [0.93-1.00]
BMI	Species Veillonella_unclassified	DMP	1.25 [1.04–1.49]
T2D	Species Veillonella_unclassified	DMP	1.08 [1.01–1.16]
Genus Faecalibacterium	T2D	DMP	1.07 [1.00-1.13]
BMI	Genus Faecalibacterium	DMP	0.86 [0.78–0.95]
BMI	Genus Sutterellaceae_unclassified	DMP	1.20 [1.03–1.40]
T2D	Genus Sutterellaceae_unclassified	DMP	1.08 [1.01–1.16]
Family Porphyromonadaceae	BMI	MibioGen	1.03 [1.00-1.05]
Family Porphyromonadaceae	T2D	MibioGen	1.09 [1.00-1.19]
Genus LachnospiraceaeUCG004	BMI	MibioGen	0.96 [0.93-1.00]
Genus LachnospiraceaeNC2004group	T2D	MibioGen	0.94 [0.89–0.99]
BMI	Genus Lachnoclostridium	MibioGen	1.17 [1.09–1.25]
T2D	Genus Lachnoclostridium	MibioGen	1.03 [1.00-1.06]

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