Fig. 2
From: Gut microbiome links obesity to type 2 diabetes: insights from Mendelian randomization
The bidirectional causal effects between the gut microbiome, body mass index (BMI), and type 2 diabetes (T2D). (A) Causal effects of the GM on T2D; (B) Causal effects of T2D on the GM; (C) Causal effects of the GM on BMI (OR < 1); (D) Causal effects of the GM on BMI (OR > 1); (E) Causal effects of BMI on the GM (OR < 1); (F) Causal effects of BMI on the GM (OR > 1). The blue lines represent negative correlation, the red lines represent positive correlation, and the arrows represent the direction of effects. DMP: the Dutch Microbiome Project; OR: odds ratio