Table 3 Mutations in OprD and down-regulated levels of OprD mRNA
Strains | Amino acid changes | Position of premature termination | Insertion sequence | mRNA relative down-regulated level |
|---|---|---|---|---|
CROPA-01 | D43N, S57E, S59R, W55-G90 | none | IS256 | 65.66 |
CROPA-02 | T103S, K115T, F170L, E185Q, P186G, V189T, R310E, A315G, G425A | none | none | 118.89 |
CROPA-03 | T103S, K115T, F170L | 427STOP | none | 291.52 |
CROPA-04 | V127L, E185Q, P186G, V189T, E202Q, I210A, E230K, S240T, N262T, T276A, A281G, K296Q, Q301E, R310E, G312R, A315G, L347M, S373Q deletions, 375–383, S403A, P405-G425 | 426STOP | none | 0.21 |
CROPA-05 | D43N, S57E, S59R, E202Q, I210A | 228STOP | none | 383.01 |
CROPA-06 | D43N, S57E, S59R, E202Q, I210A, E230K, S240T, N262T, A267S, A281-K338 | 339STOP | none | 0.41 |
CROPA-07 | 1–82 deletions | none | none | 4.56 |
CROPA-08 | D43N, S57E, S59R, E202Q, I210A, E230K, S240T, N262T, A267S, A281G, K296Q, Q301E, R310G | 343STOP | none | 1.43 |
CROPA-09 | T103S, K115T, F170L | 424STOP | none | 0.38 |
CROPA-10 | T103S, P109Q | 110STOP | none | 3.3 |
CROPA-11 | D43N, S57E, S59R | 73STOP | none | 59.93 |