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Table 1 In vitro activities of tested antibiotics against 100 A. baumannii strains

From: Investigation of the in vitro antimicrobial activity of eravacycline alone and in combination with various antibiotics against MDR Acinetobacter baumanni strains

Antibiotics

MIC (µg/ml)

 

Serum concentration (µg/mL)

 

MIC range

%50

%90

MIC50/90

%R

 

TOB

0.25->256

64–128

256 - >256

1/4

%68 (68)

4–10 [26]

LVX

< 0.125-256

8–16

64–128

1/8

%95 (95)

6.4 [27]

CPM

4->256

128–256

256 - >256

1/2

%98 (98)

39.1 [28]

MEM

1->256

64–128

128–256

1/2

%99 (99)

26 [29]

CST

< 0.125->256

0.25–0.5

32

1/128

%24 (24)

2 [30]

ERV

0.25-32

2–4

4–8

1/2

*

1–10 [31]

  1. Note: *According to the CLSI 2022 guideline, eravacycline susceptibility data for tested bacteria has not been established. TOB, tobramycin; LVX, levofloxacin; CPM, cefepime; MEM, meropenem; CST, colistin; ERV, eravacycline. R, resistance