Table 2 Comparison of baseline characteristics of patients between targeted group and empiric group
Characteristics | mNGS | Culture | p value |
|---|---|---|---|
N = 52 | N = 54 | ||
Sex, male, n (%) | 35 (67.3) | 37 (68.5) | 1 |
Age, median (IQR), years | 58.0 (33.0–64.0) | 63.0 (44.0–67.0) | 0.328 |
Medical history | |||
Dyspnea, n (%) | 8 (15.4) | 9 (16.7) | 1 |
Diabetes, n (%) | 12 (23.1) | 15 (28.8) | 0.658 |
Hypertension, n (%) | 12 (23.1) | 21 (40.4) | 0.095 |
Smoking, n (%) | 16 (30.8) | 17 (31.5) | 0.968 |
Alcoholism, n (%) | 12 (23.1) | 17 (31.5) | 0.387 |
Imaging results | |||
Multispace involvement, n (%) | 32 (61.5) | 29 (53.7) | 0.438 |
Gas formation, n (%) | 10 (19.2) | 10 (18.5) | 1 |
DNM, n (%) | 8 (15.4) | 6 (11.1) | 0.576 |
Operation | |||
Surgical drainage, n (%) | 17 (32.7) | 20 (34.2) | 0.687 |
Ultrasound aspiration, n (%) | 35 (67.3) | 34 (65.8) | |
Laboratory results | |||
CRP, median (IQR), mg/L | 158.7 (134.8, 170.4) | 159.6 (136.4, 165.2) | 0.691 |
WBC, median (IQR), 10^9 | 21.6 (16.0, 26.7) | 20.0 (17.3, 21.1) | 0.327 |
NLR, median (IQR) | 13.9 (12.0, 16.2) | 14.0 (8.8, 18.0) | 0.744 |
Platelet, median (IQR), 10^9 | 254.0 (200.0, 327.0) | 221.0 (199.0, 322.0) | 0.305 |
Glucose, median (IQR), mmol/L | 6.0 (5.0, 9.1) | 7.0 (6.4, 11.5) | 0.232 |
ALT, median (IQR), IU/L | 42.0 (36.0, 46.0) | 40.0 (35.0, 43.0) | 0.292 |
AST, median (IQR), IU/L | 36.0 (30.0, 41.0) | 36.0 (28.0, 48.0) | 0.726 |
Total protein, median (IQR), g/L | 67. 5(64.4, 73.2) | 62.0 (56.2, 67.6) | 0.100 |
Albumin, median (IQR), g/L | 32.7 (32.5, 38.0) | 31.2 (26.0, 35.0) | 0.147 |