Fig. 5
From: Taurultam shows antiviral activity against SARS-CoV-2 and influenza virus
Taurultam benefit for the treatment of coinfection with influenza A virus and SARS-CoV-2. (A) Flow chart of the coinfection experiment. (B) Effect of taurultam on the survival rate of BALB/c mice coinfected with H1N1-UI182 and SARS-CoV-2/C57MA14. (C) Lung tissues of mice from each group infected with H1N1-UI182 and the respective histopathological results (HE staining) of lung tissue sections at 2 dpi and 4 dpi. (D) Pathology scores of the lung tissues of the mice in each group. (E-F) Effects of taurultam on the viral loads of SARS-CoV-2 and H1N1 in mouse turbinates at 2 dpi and 4 dpi. (G) Effects of taurultam on the body weight of golden hamsters coinfected with H1N1-UI182 and Omicron BF.7. (H) Lung tissues of golden hamsters and histopathological results (HE staining) of lung tissue sections at 3 dpi. (I-J) Lung indices and pathology scores of lung tissues from golden hamsters in each group