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Table 7 |MIC of antibiotics and efflux for the M. simiae isolates

From: Analysis of relative genes expression and mutation of pstB and efpA efflux pumps in Mycobacterium simiae isolates from suspected tuberculosis patients by using quantitative Real-time PCR

Isolate

MOX*

CLR*

LIN*

EB*

EfpA

PstB

Fold Change

Fold Change

(µg/mL)

(µg/mL)

(µg/mL)

(µg/mL)

efpA gene

PstB

NTM10

4(R)

2

32(R)

8(R)

3.7

2

3.7

2

NTM20

8(R)

2

32(R)

8(R)

1.91

3.15

3.15

1.9

NTM28

4(R)

2

64(R)

64(R)

5.6

0.91

5.6

0.91

NTM44

16(R)

2

32(R)

64(R)

5.8

0.88

5.8

0.88

NTM100

4(R)

2

64(R)

4

4.1

1.2

4.1

1.2

NTM102

4(R)

2

32(R)

2

4

1.11

4

1.11

NTM315

8(R)

2

64(R)

4

3.7

1

3.7

1

NTM342

32(R)

2

32(R)

2

3.5

2.1

3.5

2.1

NTM23

32(R)

32(R)

64(R)

32(R)

0.9

0. 61

0.9

0. 61

NTM51

2

2

4

2

1.3

0.32

0.85

0. 72

NTM54

2

8

4

2

2

1

1.1

0.9

NTM50

2

8

4

4

1.3

3.3

3.7

2

NTM49

2

4

8

2

0.9

1.7

3.15

1.9

NTM221

2

4

4

2

1.5

1.7

5.6

0.91

NTM115

2

4

4

2

1.6

1.3

5.8

0.88

P value

      

P = 0.006

P = 0. 391