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Fig. 8 | BMC Microbiology

Fig. 8

From: Therapeutic potential of a newly isolated bacteriophage against multi-drug resistant Enterococcus faecalis infections: in vitro and in vivo characterization

Fig. 8

In vivo study of phage ZAT1 in mouse model. (A) Viable count of E. faecalis in mice blood samples at different time intervals after injection of the infective microorganism with and without injection of different MOIs of phage solution after 1 h. (B) The change in log10 E. faecalis count in mice blood samples at different time intervals after injection of the infective microorganism with and without injection of different MOIs of phage solution after 1 h. (C) Survival rate of negative control (+), positive control (infection) (â–²), treated group at MOI = 10 (â—¼), treated group at MOI = 1 (×), treated group at MOI = 0.1 (⬤). (D) The state of health score: 5: normal health; 4: slight illness, defined as lethargy and ruffled fur; 3: moderate illness, defined as severe lethargy, ruffled fur, and hunched back; 2: severe illness, with the above signs plus exudative accumulation around partially closed eyes; 1: a moribund state; 0: death

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BMC Microbiology

ISSN: 1471-2180

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