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Table 1 Comparison average transfers until clinical resistance

From: Fluoroquinolone-specific resistance trajectories in E. coli and their dependence on the SOS-response

Fluoroquinolone

MG1655

ΔrecA

p-value MG1655 vs. ΔrecA

Ciprofloxacin

7.7 ± 0.6

17 ± 5.3

0.0385

Enrofloxacin

5.3 ± 0.6

14.3 ± 2.5

0.00380

Levofloxacin

6.7 ± 1.2

11.3 ± 3.2a

0.0771

Moxifloxacin

3.3 ± 0.6

7.7 ± 2.5

0.0438

  1. The table lists the average transfers ± standard deviation until the strains reached the resistance breakpoint according to the EUCAST/CLSI guidelines (see S1 in the supplementary data). Statistical testing was performed using a linear model comparing at which transfer clinical resistance occurred for wildtype and mutants. One replicate could not reach the resistance breakpoint until the experiment ended, indicated bya
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BMC Microbiology

ISSN: 1471-2180

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