Fig. 4
From: A strategy for controlling Hypervirulent Klebsiella pneumoniae: inhibition of ClpV expression
The clpV gene deletion alters the transcriptome of hypervirulent Klebsiella pneumoniae. (A) The Volcano diagram of DEGs between WT and ΔclpV strains. (B) The top 20 GO enrichment analyses of DEGs. (C) The top 15 KEGG enrichment analyses of DEGs. (D) The expression levels of iucA, peg-344, rmpA, iroB, fimA, and entA with RT-qPCR and RNA-seq, Significance was assessed using an unpaired t-test. DEGs: differentially expressed genes. WT: wild-type strain. ΔclpV: clpV gene deletion strain. C-ΔclpV: clpV gene complementary strain. *P < 0.05, **P < 0.01, ***P < 0.001, **** P<0.0001