Fig. 3

Effect of n-3/n-6 PUFA ratio on the lipid metabolites in the liver. A pie chart (A) shows biochemical categories of identified metabolites. Significant differential metabolites screened by Orthogonal Partial Least Squares Discriminant Analysis (OPLS-DA) (VIP > 1, and P < 0.05) are shown in an S-plot in the prepartum (B) and the postpartum (D) period, with the blue and red dots indicating VIP values greater than or equal to and less than 1, respectively. The biochemical categories of differential metabolites of prepartum and postpartum are demonstrated in (C) and (E), respectively. (F) Venn diagram of the shared differential metabolites in the prepartum and postpartum period. (G) The content of all shared differential metabolites is expressed as mean ± SEM. (H) The content of lipopolysaccharide (LPS) in the liver. *P < 0.05; ns, not significant