Isolates | Mean MIC ± SD (µg/ml) | Number of passages | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |
St.L.1* | 3.12 | 3.1 | 3.1 | 5 | 5 | 6.2 | 6.25 | 6.2 | 10 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 12.5 | 20 | 20 | 25 | > 30 |
St.L.2 | 8.3 ± 3.6 | 6.2 | 6.2 | 10 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 20 | 12.5 | 20 | 20 | 20 | 25 | 20 | > 30 |
St.A | 6.25 | 5 | 5 | 6.2 | 10 | 6.2 | 6.2 | 10 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 20 | 20 | 20 | 20 | 25 | > 30 |
KP.2 | 7.2 | 6.2 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 20 | 12.5 | 20 | 25 | 20 | 25 | 20 | 25 | 25 | > 30 |
KP.1* | 6.25 | 5 | 5 | 10 | 6.2 | 10 | 6.2 | 10 | 10 | 10 | 20 | 20 | 20 | 20 | 25 | 20 | 20 | 25 | 25 | 30 | > 30 |
Ps.1 | 6.25 ± 5.4 | 5 | 6.2 | 10 | 6.2 | 6.2 | 6.2 | 10 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 20 | 20 | > 30 |
Ps.2 | 6.25 ± 5.4 | 5 | 5 | 6.2 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 12.5 | 20 | 20 | 25 | 20 | 20 | 25 | 25 | > 30 |
EC.1 | 6.25 ± 5.4 | 5 | 5 | 6.2 | 6.2 | 10 | 10 | 10 | 12.5 | 10 | 10 | 12.5 | 12.5 | 12.5 | 12.5 | 20 | 20 | 25 | 25 | 25 | > 30 |
EC.2 | 6.25 ± 5.4 | 5 | 5 | 6.2 | 6.2 | 10 | 10 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 20 | 20 | 20 | 25 | > 30 |
AB | 5.2 ± 1.8 | 3.1 | 5 | 5 | 6.2 | 6.25 | 6.2 | 10 | 10 | 10 | 12.5 | 10 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 20 | 20 | 25 | > 30 |
St. M | 2.56 ± 0.9 | 1.5 | 3.1 | 3.2 | 6.2 | 6.25 | 10 | 10 | 12.5 | 12.5 | 12.5 | 12.5 | 20 | 12.5 | 12.5 | 20 | 20 | 20 | 25 | 25 | > 30 |