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Table 1 Determination of Minimum Inhibitory Concentration (MIC) of silver nanoparticles (AgNPs) against tested gram-positive and gram-negative isolates after each of twenty consequent culture steps

From: Genetic determinants of silver nanoparticle resistance and the impact of gamma irradiation on nanoparticle stability

Isolates

Mean MIC ± SD (µg/ml)

Number of passages

 

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

St.L.1*

3.12

3.1

3.1

5

5

6.2

6.25

6.2

10

10

10

12.5

10

12.5

12.5

12.5

12.5

20

20

25

> 30

St.L.2

8.3 ± 3.6

6.2

6.2

10

10

10

12.5

10

12.5

12.5

12.5

20

12.5

20

12.5

20

20

20

25

20

> 30

St.A

6.25

5

5

6.2

10

6.2

6.2

10

10

10

12.5

10

12.5

12.5

12.5

20

20

20

20

25

> 30

KP.2

7.2

6.2

10

10

12.5

10

12.5

12.5

12.5

20

12.5

20

12.5

20

25

20

25

20

25

25

> 30

KP.1*

6.25

5

5

10

6.2

10

6.2

10

10

10

20

20

20

20

25

20

20

25

25

30

> 30

Ps.1

6.25 ± 5.4

5

6.2

10

6.2

6.2

6.2

10

10

10

12.5

10

12.5

12.5

12.5

12.5

20

12.5

20

20

> 30

Ps.2

6.25 ± 5.4

5

5

6.2

10

12.5

10

12.5

12.5

12.5

20

12.5

12.5

20

20

25

20

20

25

25

> 30

EC.1

6.25 ± 5.4

5

5

6.2

6.2

10

10

10

12.5

10

10

12.5

12.5

12.5

12.5

20

20

25

25

25

> 30

EC.2

6.25 ± 5.4

5

5

6.2

6.2

10

10

10

10

12.5

10

12.5

12.5

12.5

20

12.5

20

20

20

25

> 30

AB

5.2 ± 1.8

3.1

5

5

6.2

6.25

6.2

10

10

10

12.5

10

12.5

12.5

12.5

20

12.5

20

20

25

> 30

St. M

2.56 ± 0.9

1.5

3.1

3.2

6.2

6.25

10

10

12.5

12.5

12.5

12.5

20

12.5

12.5

20

20

20

25

25

> 30

  1. *Bacterial isolates selected for whole genome sequence