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Table 1 Baseline characteristics of study population with respect to cases and controls as well as B/F ratio cut-off

From: Correlation of gut microbial diversity to sight-threatening diabetic retinopathy

N = 54

Controls (n = 21)

[DM without DR]

Cases (n = 33)

[STDR]

p

B/F Ratio < 1.05 (n = 24)

B/F Ratio ≥1.05 (n = 30)

p

Age, mean ± SD

57.50 ± 7.60

57.45 ± 8.19

0.982

60.04 ± 6.68

56.27 ± 8.51

0.082

Men N (%)

13 (61.90)

22 (66.66)

0.724

15 (62.50)

20 (66.67)

0.752

Duration of DM, mean ± SD

13.96 ± 5.99

14.17 ± 9.52

0.929

14.38 ± 5.61

13.93 ± 9.51

0.845

FBS, mean ± SD

156.90 ± 65.89

154.86 ± 70.61

0.916

149.29 ± 77.64

162.33 ± 58.29

0.484

PPBS, mean ± SD

207.64 ± 86.55

203.07 ± 88.48

0.853

200.50 ± 101.28

208.90 ± 72.36

0.724

HbA1c, mean ± SD

7.49 ± 1.48

7.48 ± 1.67

0.982

7.36 ± 1.70

7.64 ± 1.32

0.499

Height, mean ± SD

162.24 ± 12.79

162.74 ± 13.68

0.894

160.46 ± 11.04

164.93 ± 12.83

0.499

Weight, mean ± SD

69.34 ± 13.29

69.58 ± 13.91

0.950

67.48 ± 10.93

72.17 ± 13.76

0.180

BMI, mean ± SD

26.53 ± 5.52

26.44 ± 5.99

0.956

26.38 ± 4.68

26.76 ± 5.93

0.799

Vegetarian, N (%)

7 (33.33)

14 (42.42)

0.508

5 (20.83)

16 (53.33)

0.016

Associated systemic diseases

(Based on history & medications)

      

Hypertension, N (%)

9 (42.86)

22 (66.66)

0.088

13 (54.17)

18 (60.00)

0.670

Cardiovascular Disease, N (%)

6 (28.57)

8 (24.24)

0.726

4 (16.67)

10 (33.33)

0.169

Dyslipidemia, N (%)

3 (14.29)

3 (9.09)

0.557

4 (16.67)

2 (6.67)

0.250

  1. SD: Standard Deviation; DM: Diabetes Mellitus; DR: Diabetic Retinopathy; B/F Ratio: Bacteroidetes/Firmicutes relative abundance ratio; BMI: Body Mass Index; HbA1c: Glycosylated Haemoglobin; FBS: Fasting Blood Sugar; PPBS: Post-Prandial Blood Sugar; Cases: Subjects with sight-threatening diabetic retinopathy (STDR); Controls: Subjects with diabetes mellitus, but no diabetic retinopathy
  2. Patient characteristics were summarized and compared using descriptive statistics and univariate analysis