Table 2 Quinolone resistance mechanisms and sequence types among broiler (n = 5) and human (n = 13) isolates carrying acquired quinolone resistance genes
From: Comparative genomics of quinolone-resistant Escherichia coli from broilers and humans in Norway
Specimen | Sample ID | CIP* MIC mg/L | NAL* MIC mg/L | GyrA | ParC | No. of mutations | Acquired gene | Sequence type (ST) | |
|---|---|---|---|---|---|---|---|---|---|
BROILER | meat | 2014-01-5749 | 2 | 256 | S83L | Â | 1 | qnrS1 | ST453 |
caecum | 2014-01-6924 | 1 | 64 | S83L | Â | 1 | qnrS1 | ST453 | |
caecum | 2014-01-7234 | 1 | 64 | S83L | Â | 1 | qnrS1 | ST453 | |
caecum | 2014-01-7375 | 2 | 128 | S83L | Â | 1 | qnrS1 | ST453 | |
caecum | 2014-01-5792 | 0.25 | 64 | S83L | Â | 1 | qnrB19 | ST349 | |
HUMAN | blood | Q03-42 | 4 | 256 | S83L | S58I | 2 | aac(6’)-Ib-cr | ST131 |
blood | Q03-33 | 1 | 128 | S83L |  | 1 | aac(6’)-Ib-cr | ST136 | |
blood | Q02-32 | 4 | 64 |  |  | 0 | aac(6’)-Ib-cr, qnrB1 | ST12 | |
blood | Q02-58 | 0.50 | 8 | Â | Â | 0 | qnrB19 | ST778 | |
stool | E8-09 | 0.25 | 8 | Â | Â | 0 | qnrB19 | ST10 | |
stool | E7-51 | 0.12 | 4 | Â | Â | 0 | qnrB19 | ST3877 | |
UTI* | Q01-81 | 16 | 256 | S83L, D87N | S80I | 3 | qnrB19 | ST162 | |
UTI* | Q04-11 | 8 | 256 | S83L, D87N | S80I | 3 | qnrB5 | ST162 | |
blood | Q02-39 | 1 | 16 | Â | Â | 0 | qnrS1 | ST10 | |
blood | Q02-30 | 0.25 | 4 | Â | Â | 0 | qnrS1 | ST14 | |
blood | Q01-38 | 0.50 | 8 | Â | Â | 0 | qnrS1 | ST4434 | |
stool | E4-64 | 0.25 | 32 | Â | Â | 0 | qnrS1 | ST10 | |
stool | E7-61 | 4 | 256 | S83L | Â | 1 | qnrS1 | ST117 | |