Table 1 Overview of the chromosomal point mutations causing quinolone resistance by amino acid substitution in the Escherichia coli isolates (n = 190) from broilers and from humans

Broiler

65

1

S83L

3

1

D87N

1

1

T492C

22

2

S83L

D475E

8

2

S83L, D87N

1

3

S83L

L488M, A512T

Human

9

0

42

1

S83L

2

1

D87G

1

1

S83A

5

2

S83L, D87N

2

2

S83L

S458A

2

2

S83L

A426V

2

2

S83L

D475E

1

2

S83L

S58I

1

2

S83L

E84G

9

3

S83L, D87N

S80I

1

3

S83L, D87G

S58I

1

3

S83L, D87N

S80R

1

3

S83L, D87N

S58I

1

3

S83W

V467L

E84K

4

4

S83L, D87N

S58I

L416F

3

4

S83L, D87N

S58I, S80I

1

4

S83L, D87N

S80I

S458A

1

5

S83L, D87N

S58I, S80I

L416F

1

5

S83L, D87N

S58I, S80I

E460K