Fig. 1

Biodiversity and Compositional Profile of Bile Microbiota. (A) Observed OTUs in both groups. (B) Venn Diagram of Overlaps in Bile Microbiota Composition Based on OTUs. Beta-diversity of bile microbiome based on PCA, R²=0.0422 (C), PCoA Weighted Unifrac distance, R²=0.0475 (D), PCoA Unweighted Unifrac distance, R²=0.0429 (E), NMDS, R²=0.0422 (F). OTU, operational taxonomic unit; PCA, principal component analysis; PCoA, principal coordinate analysis; NMDS, nonmetric multidimensional scaling