Skip to main content
Fig. 2 | BMC Microbiology

Fig. 2

From: Bifidobacterium longum SX-1326 ameliorates gastrointestinal toxicity after irinotecan chemotherapy via modulating the P53 signaling pathway and brain-gut axis

Fig. 2

B. longum SX-1326 in combination with irinotecan upregulates the expression of apoptotic proteins to exert anti-tumor effects. A Monitor the number of mouse tumors; B Detection of expression of p53-induced apoptosis signaling pathway protein in tumor tissue by WB; C-F WB results of p-p53, Bax and Bcl-2 in tumor tissues were quantified using ImageJ; H. Detection of expression of Cleaved Caspase-3 in tumor tissue by WB; I. WB results of Cleaved Caspase-3 in tumor tissues were quantified using ImageJ. Experimental group: M: colorectal cancer model group; B: Bifidobacterium longum SX-1326 group; I: Irinotecan chemotherapy group; U: Bifidobacterium longum SX-1326 plus irinotecan dosing group. Data are expressed as mean ± SD, *p < 0.05, **p < 0.01

Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us