Fig. 2

Maximum-likelihood tree of 54 isolates based on whole genome sequences (A) and genes (FKS2, ZCF15, and FKS1) that had significantly higher mutation rates in echinocandin non-susceptible isolates of ST7 (B). Echinocandin susceptibility and amino acid substitution/deletion of each isolate were annotated. Well-known FKS hotspot mutations were colored in red