Fig. 3

Schematic diagram of amino acid substitution panels in multidrug-resistant non-typeable Haemophilus influenzae isolates. Blue box, ampicillin-resistance; green box, amoxicillin-clavulanate resistance; beige box, cefuroxime resistance; red box, levofloxacin resistance; gray box, trimethoprim-sulfamethoxazole resistance; purple box, azithromycin resistance; orange box, tetracycline resistance. Substitutions associated with high-level drug resistance were marked with an asterisk