Fig. 2

Isolates with high-level resistance to cefuroxime, levofloxacin, and trimethoprim-sulfamethoxazole. (A) A Venn diagram for NTHi isolates with cefuroxime MIC ≧64 μg/mL and both levofloxacin and trimethoprim-sulfamethoxazole MICs ≧32 μg/mL is shown. (B) A network clustering of mutation for high-level levofloxacin resistance is shown. The size of the circles and width of the lines are proportional to the frequency of each mutation and the connection of two mutations, respectively