Fig. 1

DRBD2 and yeast Gbp2 alignment and secondary structure maps. In green is the first RRM domain, in blue the second RRM domain, present only in Gbp2 and in yellow the third RRM domain. In bold and underlined the amino acids that are part of the secondary structure (S - β-sheets and H - α-helixes). The Serine residues in red are the phosphorylation sites of DRBD2. Symbols - “*” (asterisk) fully conserved amino acid residues; “:“ (colon) conservation between groups of strongly similar properties; “.” (period) conservation between groups of weakly similar properties